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Artificial Intelligence, Machine Learning, Causality & Biomedical Informatics

A research group at the University of Crete, founded in 2006 and led by Prof. Ioannis Tsamardinos. We combine theoretical, algorithmic and applied research in causal discovery and machine learning, with collaborations across biology, medicine and industry.

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Automated Machine Learning & Biomedical Applications

We develop state-of-the-art AutoML methods and apply them to challenging biomedical problems — cancer screening, diabetes diagnosis, and multi-omics data analysis.

Our Publications

Automated Causal Discovery

We are building software that takes your data and automatically discovers, explains and visualizes the plausible causal relationships, supporting better decisions and root-cause analysis through a natural-language interface.

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Recent Publications
2025
Biza, Konstantina, Ntroumpogiannis, Antonios, Triantafillou, Sofia, Tsamardinos, Ioannis — Discovery Science
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Tercan, Bahar, Apolonio, Victor H, Chagas, Vinicius S, Wong, Christopher K, Lee, Jordan A, Yau, Christina, Benz, Christopher C, Stuart, Joshua M, Karlberg, Brian J, Ellrott, Kyle, others — STAR protocols
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2024
Myrtakis, Nikolaos, Tsamardinos, Ioannis, Christophides, Vassilis — The Provenance of Elegance in Computation-Essays Dedicated to Val Tannen (2024)
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Ellrott, Kyle, Wong, Chris K, Yau, Christina, Castro, Mauro A, Lee, Jordan, Karlberg, Brian, Grewal, Jasleen K, Lagani, Vincenzo, Tercan, Bahar, Friedl, Verena, others — Cancer Research
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Nguyen, Olav Toai Duc, Fotopoulos, Ioannis, Markaki, Maria, Tsamardinos, Ioannis, Lagani, Vincenzo, R{\o}e, Oluf Dimitri — JTO clinical and research reports
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Paterakis, George, Fafalios, Stefanos, Charonyktakis, Paulos, Christophides, Vassilis, Tsamardinos, Ioannis — ACM Transactions on Knowledge Discovery from Data
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Nguyen, Olav Toai Duc, Fotopoulos, Yannis, N{\o}st, Therese Haugdahl, Markaki, Maria, Lagani, Vincenzo, Tsamardinos, Ioannis, R{\o}e, Oluf Dimitri D — American Society of Clinical Oncology
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Charonyktakis, Pavlos, Antoniou, Grigoris, Adamou, Marios, Doyle, Michael, Batsakis, Sotiris, Tsamardinos, Ioannis — 2024 15th International Conference on Information, Intelligence, Systems \& Applications (IISA)
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